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Prevalence and risk factors for sessile serrated lesions in an average risk colorectal cancer screening population

Journal of Gastroenterology and Hepatology Jan 28, 2021

Lui RN, Kyaw MH, Lam TYT, et al. - In an average colorectal cancer (CRC) risk screening population of Chinese individuals, researchers conducted this case-control study to examine the prevalence and potential risk factors of sessile serrated lesions (SSLs) in these patients. Using multivariable logistic regression, those with SSLs were compared against controls without these lesions to find possible risk factors. In this investigation, the prevalence of SSLs is reported to be 1.4% out of Of 12,039 asymptomatic screening subjects. Independent risk factors for SSLs were age ≥ 66 years, smoking, and diabetes mellitus. The results include important new evidence that should be taken into account in the design of region‐specific SSL surveillance programs with the ultimate objective of reducing the risk of CRC.

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