Alidousty C, Duerbaum N, Wagener‐Ryczek S, et al. - Two ALK + (anaplastic lymphoma kinase) lung cancer patient cohorts (TP53 wild‐type/TP53 mutated) were examined by investigators in previous studies in terms of copy number changes and it was identified that mainly genetically stable genomes were present in all patients belonging to the TP53 wild‐type group, with one exception demonstrating chromosomal instability and amplifications of various gene loci, including TERT (telomerase reverse transcriptase), therefore, researchers focused on TERT amplifications prevalence in these ALK + lung cancer patients. For this purpose, they assessed an independent cohort of 109 ALK translocated cases. They further evaluated the copy numbers of numerous cancer‐relevant genes as well as other genetic aberrations. Using FISH analyses, prevalence of TERT amplifications was ascertained. As per findings, amplification of TERT was harbored by five (4.6%) of all 109 analyzed ALK + patients; the presence of genetically unstable genomes was also evident in these patients. As per this preliminary work, ALK + adenocarcinomas should be assessed in the context of their genomic background so that patients' individual course of disease can be more clearly understood and predicted.