Sartorius B, Cano J, Simpson H, et al. - Driven by global targets to eliminate soil-transmitted helminths as a public health problem, control programs have been rapidly rolled out by governments using school and community-based platforms. Given the necessity for quantification of impact and identification of remaining high-risk areas to justify and target ongoing investment, researchers sought to determine regional progress towards these targets. They used a Bayesian space–time hierarchical model to perform a continental-scale ecological analysis measuring the effects of known environmental, socioeconomic, and control-related factors on the prevalence of soil-transmitted helminths. Data from 26,304 georeferenced surveys, spanning 3,096 (60%) of the 5,183 programmatic implementation units, was incorporated. Per findings, the prevalence of soil-transmitted helminths has reduced among children aged 5–14 years in sub-Saharan Africa, from 44% in 2000 to 13% in 2018, driven by sustained delivery of preventive chemotherapy, improved sanitation, and economic development. However, an estimated prevalence of moderate-to-heavy intensity infection was still reported in 1,301 (25%) of 5183 implementation units exceeding the 2% target threshold in 2018, largely concentrated in nine countries (in 1,026 [79%] of 1301 implementation units): Nigeria, Democratic Republic of the Congo, Ethiopia, Cameroon, Angola, Mozambique, Madagascar, Equatorial Guinea, and Gabon.