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Prevalence and incidence of young onset dementia and associations with comorbidities: A study of data from the French national health data system

PLoS Medicine Oct 08, 2021

Carcaillon-Bentata L, Quintin C, Boussac-Zarebska M, et al. - As per estimates generated using data from the French national health data system for 76% of the French population, there were about 24,000 and nearly 5,300 persons with prevalent and incident YOD (young onset dementia), respectively, in France in 2016.

  • Among persons aged 40 to 64 years, YOD prevalence and incidence were estimated, and the contribution of comorbidities to YOD incidence was assessed.

  • Standardized prevalence rate and incidence rate were reported to be 109.7/100,000 and 24.4/100,000 person-years, respectively, and were higher among males compared with females.

  • Men had a higher YOD frequency vs women, which may be partly because of the higher prevalence of cardiovascular and neurovascular diseases and substance abuse disorders in men.

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