Ha J, Lee MJ, Kim SJ, et al. - Given that patients with cancer carry an increased risk of acute ischemic stroke but there is no clarity regarding the mechanism behind cancer-related stroke, researchers investigated the presence of associated venous thromboembolism and arterial thromboembolism as well as their clinical influence on patients with cancer-associated stroke. Using Doppler sonography, analysis of patients with embolic stroke of undetermined source with or without cancer was done for venous thromboembolism (deep vein thrombosis [DVT] and/or pulmonary embolism) and arterial thromboembolism in order to ascertain the presence of lower-extremity DVT and the microembolic signal of the symptomatic cerebral circulation, respectively. Findings revealed an elevated risk of associated venous thromboembolism and arterial thromboembolism in patients with cancer-related embolic stroke of undetermined source. One-year survival in these patients was significantly negatively influenced by the presence of associated venous thromboembolism and arterial thromboembolism. These findings may enhance risk stratification in these patients.