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Prevalence and impact of risk factors for poor asthma outcomes in a large, specialist-managed patient cohort: A real-life study

Journal of Asthma and Allergy Sep 28, 2019

Tomisa G, et al. - A large cohort of asthmatic patients treated by respiratory specialists in Hungary was examined in this cross-sectional, non-interventional real-life study to determine the level of symptom control and the frequency of specific risk factors for poor asthma outcomes. Researchers used the Global Initiative for Asthma guideline to evaluate asthma control and risk factors. Overall 12,743 patients were registered, of these, well-controlled asthma was present in 36.0%, partially controlled in 29.29%, and uncontrolled in 34.71%. Rhinitis/sinusitis (66.84%), cardiovascular diseases (43.81%), and gastroesophageal reflux disease (20.11%) were documented as the most commonly experienced comorbidities. In this real-world large patient cohort, a significant impact of the presence of risk factors for poor asthma outcomes, listed by the Global Initiative for Asthma document, on actual control level was evident; the highest influence was exerted by high short-acting beta agonist use, previous severe exacerbation, incorrect inhaler technique, persistently low forced expiratory volume in 1 s, and poor adherence to treatment.
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