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Prevalence and features of impaired glucose tolerance in young underweight Japanese women

Journal of Clinical Endocrinology and Metabolism Feb 03, 2021

Sato M, Tamura Y, Nakagata T, et al. - Researchers conducted this cross-sectional study to examine the prevalence and features of impaired glucose tolerance (IGT) in young Japanese underweight women. Fifty-six normal weight and 98 underweight young Japanese women were recruited and their glucose tolerance levels were evaluated using an oral glucose tolerance test. Then, in underweight women, the clinical characteristics associated with normal glucose tolerance (NGT) and IGT were compared. The prevalence of IGT was higher in young, underweight Japanese women than in normal-weight women. The underweight women with IGT displayed impaired early-phase insulin secretion, low fitness levels, and decreased whole-body and adipose tissue insulin sensitivity levels.

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