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Prevalence and factors associated with multidrug/rifampicin resistant tuberculosis among suspected drug resistant tuberculosis patients in Botswana

BMC Infectious Diseases Sep 14, 2019

Tembo BP, et al. - Researchers examined the prevalence of multidrug/rifampicin-resistant tuberculosis (MDR/RR-TB) among suspected drug-resistant tuberculosis patients in Botswana. Further, they sought for the associated factors. For this retrospective review, they obtained 2,568 medical records of suspected drug-resistant tuberculosis patients who received care at public health facilities in Botswana from January 2013, and December 2014. Multidrug/ rifampicin - resistance was identified in 139 (5.4%) cases with 1.3% among new cases and 7.7% among previously treated tuberculosis patients. This suggests a low burden of MDR/RR-TB among these patients. Findings emphasize the inclusion of an effective implementation of Directly Observation Treatment – short course strategy, continuous surveillance of drug resistance cases, prevention of the development of new cases of MDR/RR-TB and treatment of existing patients in strategies in controlling MDR/RR-TB. Strengthening TB infection control activities should be the focus of further interventions.
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