Balkhair A, et al. - In view of the challenges observed in correlation with bacteremia due to carbapenem-resistant gram-negative bacteria, researchers assessed adult patients admitted to Sultan Qaboos University Hospital between January 1, 2007 and December 31, 2016 with positive blood cultures for Klebsiella pneumoniae, Pseudomonas aeruginosa, or Acinetobacter baumannii for the burden of carbapenem and colistin resistance. Carbapenem-resistance was identified in 227 (29.8%) of 761 bacteremia cases due to these three isolates; 87.2 % were healthcare-associated. The analysis revealed an increase in the rates of carbapenem resistance in P. aeruginosa, A. baumannii, and K. pneumoniae bacteremia from 20%, 67%, and 0%, respectively, in 2007 to 25%, 86%, and 35%, respectively, in 2016. Colistin resistance was observed in 17 (7.9%) of 216 carbapenem-resistant blood isolates. They observed higher 30-day all-cause mortality among cases with carbapenem-resistant bacteremia.