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Pretreatment MRI features associated with diagnostic accuracy of post-treatment MRI after neoadjuvant chemotherapy

Clinical Radiology Mar 27, 2018

Eun NL, et al. - This research was designed to examine if pre-treatment magnetic resonance imaging (MRI) features correlate with the diagnostic accuracy of post-treatment MRI with the intention of determining pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) in individuals with breast cancer. It was found that the diagnostic accuracy of post-treatment MRI was 84.2%. The presence of peritumoural edema and HER2-positive status were prominently related to false-positive MRI results, among the pre-treatment features. A possible connection was demonstrated between pre-treatment MRI features and cancer subtypes with the diagnostic accuracy of post-treatment MRI following NAC in the study cohort.

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