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Pretreatment lymphocytopenia is an adverse prognostic biomarker in advanced-stage ovarian cancer

Cancer Medicine Jan 22, 2019

Lee YJ, et al. - The prognostic significance of lymphocytopenia in advanced-stage ovarian cancer was assessed by performing a retrospective review of 506 patients with advanced-stage ovarian cancer at Yonsei Cancer Hospital. Researchers included a neoadjuvant chemotherapy (NAC) group (N = 247) and a primary debulking surgery (PDS) group (N = 259). In both the cohorts, the absolute lymphocyte count was identified to be a significant factor when analyzed as a continuous variable. Patients with advanced-stage ovarian cancer displayed adverse prognosis in independent relation to pretreatment lymphocytopenia.

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