Presentation, treatment, and outcome of survivors of in-hospital vs out-of-hospital sudden cardiac arrest
The American Journal of Cardiology Feb 05, 2020
McDermott AT, Polsinelli VB, Wang NC, et al. - Researchers compared survivors of in-hospital (IHSCA) vs out-of-hospital (OHSCA) sudden cardiac arrest (SCA), focusing on baseline features, rates of implantable cardioverter defibrillator (ICD) implantation as well as long-term all-cause mortality. This analysis included 1,433 SCA survivors, including 807 IHSCA and 626 OHSCA, from 2002 to 2012, who were followed through February 2017. IHSCA and OHSCA patients demonstrated similar presence of SCA triggers. OHSCA was more likely related to cardiac ischemia and drug abuse, while IHSCA was more related to novel antiarrhythmic drugs. The probability of receiving an ICD was more among OHSCA survivors. A median follow-up of 3.6 years was performed among participants, during which, the deaths of 674 (47%) patients were documented. A similar survival was experienced by IHSCA and OHSCA survivors, following adjustment for unbalanced baseline features. Overall, in terms of baseline characteristics, potential SCA triggers and treatment interventions, disparities were evident between survivors of IHSCA and OHSCA, however, both groups had comparable adjusted survival.
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