Zhu CN, et al. - Researchers performed this study in order to determine the role of melena in speculating bleeding in the proximal small intestine among subjects with obscure gastrointestinal bleeding (OGIB). It was found that 56.1% of patients with melena reported a bleeding source within the proximal small intestine vs 34.8% for those without. Results disclosed that the presence of melena doubled the odds of finding a bleeding site within the proximal small intestine among patients with OGIB, and deep enteroscopy, if performed before a capsule study, ought to begin with an antegrade approach in these patients.