Miyamura T, Sakamoto N, Ishida K, et al. - Researchers analyzed 133 consecutive patients who received surgery for lung cancer in Japan from January 2009 to December 2010 to investigate if expression of heat shock protein 47 (HSP47), a collagen-binding protein, is related to the risk of postoperative recurrence of lung cancer. HSP47-positive cancer cells were present in 67 patients (50.4%), and a greater number of HSP47-positive fibroblasts were detected in 91 patients (68.4%). According to the findings, a risk for recurrence of lung cancer post-surgery was conferred by the presence of a high number of HSP47-positive fibroblasts in the cancer stroma.