Rivera N, et al. - Researchers investigated whether a higher prevalence of sleep-disordered breathing (SDB) and higher inflammatory biomarkers (blood-hsCRP and urinary-LTE4) levels could be seen among preschoolers with asthma risk (positive asthma predictive index [API]) vs those with negative API. They categorized children, aged 2 to 5 years of age and having recurrent wheezing, as positive or negative API. Using the pediatric sleep questionnaire (PSQ) and its subscale (PSQSub6), they assessed SDB. Between these groups, a similar proportion of SDB was found. In the positive vs in negative API, a higher hsCRP was detected; moreover, urinary LTE4 did not differ between groups. A significantly more post-bronchodilator percentage change in FEF25-75 was seen among preschoolers with positive API vs negative API. Based on these findings, they recommended investigating preschoolers with recurrent wheezing for the coexistence of SDB, by means of early screening methods for identifying those conditions.