Ytre-Hauge S, et al. - In this prospective cohort study, researchers explored if tumor texture parameters in endometrial cancer patients from preoperative MRI are associated with known prognostic features (deep myometrial invasion, cervical stroma invasion, lymph node metastases, and high-risk histological subtype) and to outcome. Participants were 180 patients with endometrial carcinoma included from April 2009 to November 2013 and studied until January 2017. They found high tumor entropy in apparent diffusion coefficient maps independently enabled prediction of deep myometrial invasion, and high-risk histological subtype was independently predicted by high mean of positive pixels in T₁c images. MRI-derived tumor texture parameters also independently predicted reduced survival in endometrial carcinomas, and therefore, offer a more refined preoperative risk evaluation.