Pasanen A, et al. – The purpose of this study is to figure out if preoperative analysis of L1 cell adhesion molecule (L1CAM) can improve risk assessment. The outcome suggests L1 cell adhesion molecule expression in endometrial biopsy correlates with high–risk features of endometrial carcinoma but does not significantly improve risk stratification algorithms based on traditional factors. Soluble L1 detected in the serum of patients with endometrial carcinoma does not correlate with tumoral L1CAM expression.