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Preoperative prediction of lymphovascular invasion in invasive breast cancer with dynamic contrast-enhanced-MRI-based radiomics

Journal of Magnetic Resonance Imaging Feb 21, 2019

Liu Z, et al. - In this prospective study, researchers examined the use of dynamic contrast-enhanced (DCE)-magnetic resonance imaging (MRI)-based radiomics for preoperative prediction of lymphovascular invasion (LVI) in invasive breast cancer. For this investigation, they registered 90 training cohort patients (22 LVI-positive and 68 LVI-negative) and 59 validation cohort patients (22 LVI-positive and 37 LVI-negative). In combination with the MRI axillary lymph node (ALN) status, the radiomic signature based on DCE-MRI was effective in predicting the LVI status of patients with invasive breast cancer prior to surgery. Identified independent risk factors for LVI were MRI ALN status and the radiomics signature.
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