Liu Z, Feng B, Li C, et al. - Through this prospective study of 90 training cohort patients (22 lymphovascular invasions (LVI)-positive and 68 LVI-negative) and 59 validation cohort patients (22 LVI-positive and 37 LVI-negative), researchers determined the utility of dynamic contrast-enhanced (DCE)-MRI-based radiomics for preoperative prognostication of LVI in invasive breast cancer. To construct the radiomics signature, two radiomic features were chosen. Independent risk factors for LVI were MRI axillary lymph node (ALN) status and the radiomics signature. For a model combining both, the value of the AUC was higher than that for MRI ALN status alone and comparable to that for the radiomics signature. Decision curve analysis demonstrated that the combined model added more net advantage than either feature alone. Thus, in combination with MRI ALN status, the DCE-MRI-based radiomics signature was efficient in prognosticating the LVI status of patients with invasive breast cancer prior to the surgery.