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Preoperative neuropathic pain like symptoms and central pain mechanisms in knee osteoarthritis predicts poor outcome 6 months after total knee replacement surgery

The Journal of Pain Jun 21, 2018

Kurien T, et al. - Assuming the significance of preoperative pain characteristics in osteoarthritis (OA) patients in explaining persistent pain after total knee replacement (TKR), researchers evaluated the degree of neuropathic pain symptoms and pain sensitisation via pain phenotyping OA patients into two groups based on the PainDETECT questionnaire: High PainDETECT group (scores ≥19) indicating neuropathic pain-like symptoms, Low PainDETECT group (scores <19) indicating nociceptive or mixed pain. As per findings, postoperative pain could be independently predicted with preoperative PainDETECT scores. They noted a higher risk of developing chronic postoperative pain after TKR surgery among knee OA patients with neuropathic pain like symptoms identified using the PainDETECT questionnaire.
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