Preoperative N stage evaluation in advanced gastric cancer patients using multidetector CT: Can the sum of the diameters of metastatic LNs be used for N stage evaluation?
Clinical Radiology Aug 07, 2019
You JM, Kim TU, Kim S, et al. - One hundred and twenty-seven consecutive individuals who underwent preoperative multidetector (MD) computed tomography (CT) and gastrectomy for advanced gastric cancer (AGC) were recognized by the researchers in order to contrast the diagnostic performance of total counts of metastatic lymph nodes (LN-sum) and MDCT staging in the nodal assessment of AGC individuals. In comparison to those identified in histopathological assessments, the total counts of metastatic LNs on MDCT was markedly smaller. A notable association was exhibited by LN-sum with the pathological N stage and the number of metastatic LNs. With cut-off values of 12.5 and 23.5 mm, for N stage ≥ N2 and N3, the areas under the receiver operating characteristic curve were 0.896, and 0.835 respectively. For distinguishing N0–2 vs N3, LN-sum presented better diagnostic performance vs conventional MDCT staging with significantly greater sensitivity, accuracy, PPV and NPV of LN-sum. Therefore, in evaluating the N3 stage of AGC, LN-sum may be adequately beneficial and may aid to plan relevant therapy for AGC patients.
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