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Preoperative MRI evaluation of lesion–nipple distance in breast cancer patients: Thresholds for predicting occult nipple–areola complex involvement

Clinical Radiology Apr 26, 2018

Mariscotti G, et al. - Researchers aimed to identify clinically occult nipple–areola complex (NAC) involvement using preoperative magnetic resonance imaging (MRI), to inform selection of patients eligible for nipple-sparing mastectomy (NSM) or skin-sparing mastectomy (SSM). They recognized MRI to be a valuable tool for identifying NAC+ patients; a 10-mm cut-off for lesion–NAC distance [LND] assists selection of patients for NSM, although intraoperative retroareolar tissue examination remains mandatory. The discriminating ability of Lesion-to-Nipple distance was good by receiver operating characteristic analysis.
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