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Preoperative low skeletal muscle mass as a risk factor for pharyngocutaneous fistula and decreased overall survival in patients undergoing total laryngectomy

Head & Neck Jan 24, 2019

Bril SI, et al. - Investigators analyzed 235 cases to assess the association of low skeletal muscle mass (SMM) with postoperative complexities, extended hospital stay, and short overall survival (OS) in subjects undergoing total laryngectomy (TL). Out of 235 patients, they observed 109 with low SMM, and they had more pharyngocutaneous fistulas (PCFs) and prolonged hospital stay vs those with normal SMM. They also found low SMM and high N stage as significant predictors of reduced OS. Overall, they noted low SMM as an independent predicting factor for shorter OS.

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