Preoperative computed tomography scanning for abdominal neuroblastomas is superior to magnetic resonance imaging for safe surgical planning
Pediatric Blood & Cancer Aug 16, 2019
Burnand K, Barone G, McHugh K, et al. - Through a retrospective study of 31 children with abdominal neuroblastoma (NBL) referred for surgery from January 2016 to February 2018, researchers established which imaging modality, MRI or CT, was more reliable in order to discover the extent of the disease, especially, following chemotherapy. Of the 31 children, 24 were included. In half of the patients considered for NBL resection, MRI underestimated the extent of the disease; tumor fibrosis, calcification, and chemotherapy may be the cause. Findings suggested that preoperative CT scan is the best imaging modality to identify all imaging-defined risk factors to ensure safe surgery after chemotherapy. Seventeen of 24 patients underwent surgery, and operative findings had 100% correlation with CT imaging.
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