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Preoperative C-reactive protein/albumin ratio is a significant predictor of survival in bladder cancer patients after radical cystectomy: A retrospective study

Cancer Management and Research Nov 01, 2018

Guo Y, et al. - In patients with bladder cancer following radical cystectomy (RC), authors gauged the prognostic ability of preoperative C-reactive protein (CRP)/albumin ratio (CAR) and evaluated its prognostic index value. They estimated the overall survival (OS) and progression-free survival (PFS) using the Kaplan–Meier method and Cox regression analyses in 131 patients with bladder cancer after RC between 2009 and 2015. In patients with bladder cancer after RC, CAR can be used as a new prognostic indicator of OS and PFS. For poor OS, but not for PFS, a more effective prognostic indicator can be had with combining the CAR score with pathological T staging as the CART score. Compared to other conventional clinical indices, the area under the receiver operating characteristic curve (AUC) values of CAR for OS and PFS were higher.

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