Mai RY, et al. - Researchers sought to determine whether preoperative aspartate aminotransferase-to-platelet-ratio index (APRI) score could predict the risk of posthepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC) after liver resection, and to compare the discriminatory performance of the APRI with the Child–Pugh score, model for end-stage liver disease (MELD) score, and albumin–bilirubin (ALBI) score. Enrolling 1,044 consecutive patients with HCC who underwent liver resection, they assessed the predictive discrimination of Child–Pugh, MELD, ALBI, and APRI scores for predicting PHLF according to area under the ROC curve. Outcomes suggest the superior accuracy of the APRI score in predicting PHLF in these patients than Child–Pugh, MELD, or ALBI scores.