Zasada M, et al. - In the present study, researchers tested the effectiveness of L-ascorbic acid applied in combination with no-needle and micro-needle mesotherapy in anti-aging therapy by analyzing data of 17 healthy volunteers. They used 2.5 ml of serum containing 20% L-ascorbic acid with hydrate from strawberries topically in four treatments. After micro-needle mesotherapy, the effect of the active substance on skin firmness and elasticity and the degree of hydration and skin tone was more efficient.