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Prehospital statin use and low-density lipoprotein cholesterol levels at admission in acute coronary syndrome patients with history of myocardial infarction or revascularization: Findings from the Improving Care for Cardiovascular Disease in China (CCC) project

American Heart Journal Apr 18, 2019

Xing Y, et al. - Using data from a nationwide registry (Improving Care for Cardiovascular Disease in China project), researchers examined acute coronary syndrome (ACS) patients with history of myocardial infarction (MI) or revascularization in order to assess the use of prehospital statins and low-density lipoprotein cholesterol (LDL-C) levels at admission among these subjects. Overall, 6,523 patients were analyzed, and, from the initial admission lipid testing, LDL-C levels were collected. Of these patients, 50.8% were taking lipid-lowering therapy before hospitalization, mostly statin monotherapy. Of those taking prehospital statins, 36.1% had LDL-C < 70 mg/dL vs 24.0% in those not taking prehospital statins. According to the findings, statin therapy was not received by half of these patients before admission, and even prehospital statin use did not lead to the attainment of LDL-C < 70 mg/dL in the majority of these cases. Findings point towards a significant opportunity to offer intensive statin or combination lipid-lowering therapy to these very high-risk patients.

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