Prehospital comprehensive stroke center vs primary stroke center triage in patients with suspected large vessel occlusion stroke
JAMA Aug 13, 2021
Kass-Hout T, Lee J, Tataris K, et al. - A significant, rapid, and sustained increase in endovascular therapy (EVT) rate for patients with acute ischemic stroke (AIS) was associated with the implementation of a prehospital transport policy for comprehensive stroke center triage in Chicago, with no negative associations with thrombolysis rates or times.
Among 7,709 stroke patients, 663 (mean [SD] age, 68.5 [14.9] years; 342 women [51.6%] and 321 men [48.4%]; and 348 Black people [52.5%]) with AIS arrived by emergency medical services (EMS) transport within 6 hours of stroke onset: 310 of 2,603 (11.9%) before implementation and 353 of 2,637 (13.4%) after implementation.
The EVT rate increased overall among all AIS patients and among AIS patients transported by EMS within 6 hours of onset.
According to an interrupted time series analysis of EMS-transported patients, the level change within one month of implementation was 7.15% with no slope change before or after, indicating a step rather than gradual change.
There was no change in the time to thrombolysis or the rate of thrombolysis.
There were no variations in EVT rates in patients not arriving by EMS in the 6- to 24-hour window or by interhospital transfer or walk-in, regardless of time window.
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