Sliwa K, Baris L, Sinning C, et al. - By analyzing relevant 10-year data from the European Society of Cardiology EORP ROPAC (EURObservational Research Programme Registry of Pregnancy and Cardiac disease) registry, researchers assessed maternal as well as fetal outcomes of women with uncorrected congenital heart disease (CHD). This analysis included 5,739 pregnancies in 53 countries. Experts noted that in uncorrected cases vs in corrected CHD cases, there existed marked differences between the cardiac defects, with primary shunt lesions (44.7% vs 32.4%, respectively), valvular abnormalities (33.5% vs 12.6%, respectively), and Tetralogy of Fallot and pulmonary atresia (0.8% vs 20.3%, respectively). Findings not only highlighted these marked differences among pregnant women with uncorrected CHD and those with corrected CHD, but also revealed a markedly worse outcome, especially in women with Eisenmenger syndrome and from emerging countries.