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Predictors of severe neurologic injury on ultrasound scan of the head and risk factor-based screening for infants born preterm

The Journal of Pediatrics Aug 03, 2019

Beltempo M, Wintermark P, Lemyre B, et al. - In this retrospective cohort study, researchers identified risk factors for severe neurologic injury (intraventricular hemorrhage grade 3 or greater and/or periventricular leukomalacia) diagnosed with ultrasonic scanning of the head among infants born at 300-326 weeks of gestation and compared various screening strategies. The study sample consisted of infants born at 300-326 weeks or > 326 weeks of gestation with a birth weight < 1500 g admitted to neonatal intensive care units in the Canadian Neonatal Network from 2011 to 2016. Among infants screened (285/9,221), the rate of severe neurologic injury was 3.1%. Singleton birth, 5-minute Apgar < 7, mechanical ventilation on day 1, and treatment with vasopressors on day 1 were included significant risk factors. Findings suggested that risk factor-based ultrasound scanning of head screening among infants born at 30-32 weeks of gestation may help to better optimize resources than screening based on gestational age.
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