Ito K, et al. – This study was performed to determine the predictors of postoperative non–chylous massive discharge after pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDA). The independent predictive factors for high non–chylous discharge were preoperative low levels of body mass index (BMI) and hemoglobin and intraoperative high blood loss. Improvement of preoperative general and nutritional condition might reduce the incidence of high non–chylous discharge.