Predictors of postinjury acute respiratory distress syndrome: Lung injury persists in the era of hemostatic resuscitation
The Journal of Trauma and Acute Care Surgery Aug 02, 2019
Kornblith LZ, Robles AZ, Conroy AS, et al. - Researchers sought for predictors of postinjury acute respiratory distress syndrome (ARDS) in the era of hemostatic resuscitation via analyzing prospectively collected data of 914 highest-level trauma activations who required intubation and survived more than 6 hours from 2005 to 2016 at a Level I trauma center. Outcomes revealed no independent correlation of blood and plasma transfusion with ARDS. However, a significant independent risk was noted in correlation with platelet transfusion. Further investigation is required for assessing the role of platelets however lung injury models of pulmonary platelet sequestration with peripheral thrombocytopenia may mechanistically explain their role.
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