Lubitz SA, et al. - Factors associated with oral anticoagulation (OAC) non-prescription in patients with non-valvular atrial fibrillation (AF) at elevated stroke risk were determined using NCDR PINNACLE, a United States-based ambulatory cardiology registry. Data showed that among AF patients, treatment with OAC was commonly employed for older patients at elevated stroke and low bleeding risk. However, a variety of factors associated with OAC non-prescription included reversible AF etiology; female sex; liver, renal, or vascular disease; and physician versus non-physician provider. Specifically, antiplatelet use was prevalent and associated with the highest likelihood of OAC non-prescription.