Sertic F, Chavez L, Diagne D, et al. - In order to improve patient selection for durable weaning from venoarterial extracorporeal membrane oxygenation (VA-ECMO), researchers sought for predictors of in-hospital mortality and mid-term outcomes of patients successfully weaned from VA-ECMO after support for cardiogenic shock, surviving more than 24 hours after weaning. Among 92 analyzed patients who were supported on VA-ECMO and successfully weaned between January 2013 and February 2018, the overall survival of 64.2% at hospital discharge was reported; survival was 54.6% 1-year postsupport and 51.4% 3-years postsupport. Outcomes revealed that in well-selected patients, durable ECMO weaning could be obtained with acceptable mid-term functional status. Strong predictors of in-hospital mortality after VA-ECMO weaning were previous myocardial infarction, diabetes, prolonged ECMO support, and pulmonary dysfunction. In this high-risk situation, they recommend considering other heart replacement therapies.