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Predictors of hypertensive disorders in pregnancy in women with and without polycystic ovary syndrome: Australian Longitudinal Study of Women’s Health

Clinical Endocrinology Mar 03, 2021

Khomami MB, Earnest A, Loxton D, et al. - Given that women with polycystic ovary syndrome (PCOS) are frequently reported to be at a higher risk of hypertensive disorders in pregnancy (HDP), researchers aimed at examining if and how PCOS per se affects the incidence of HDP via performing post hoc sub‐group analyses of Australian Longitudinal Study on Women’s Health by level of risk. Among a total of 14,247 participants, they identified 5,838 women as eligible for inclusion in this study. Following were the included risk factors: age, BMI, country of birth, parity, multiple pregnancy, subfertility, infertility treatment (hormonal vs. in vitro fertilization), gestational diabetes (GDM), family history of GDM and socioeconomic status. Findings suggest that risk factors other than PCOS likely associate with a higher risk of HDP in PCOS.

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