Orr SL, et al. - A population of pediatric patients visiting an infusion center for acute migraine was characterized and predictors of first-line treatment success in this population were investigated. Via performing an observational study involving a retrospective analysis of data from visits to the Cincinnati Children's Hospital infusion center for treatment of an acute migraine, researchers suggest that higher baseline headache frequency and presence of MOH could predict lower odds of treatment success after first-line intervention for pediatric migraine in the acute setting. Patients could be stratified using these predictors for treatment protocols and for planning future intervention studies.