Zucker J, et al. - Researchers sought to determine the possible risk factors for disengagement from a comprehensive HIV prevention program via retrospectively analyzing a cohort of patients initiating tenofovir–emtricitabine therapy between January 1, 2015 and November 30, 2017. Mostly African Americans (23%) and Hispanics (46%) were in the cohort. Lower retention correlated with age <30, PrEP initiation in 2017, PrEP initiation in the sexual health clinic, and PrEP same-day start; higher retention correlated with male gender at birth, transition from post-exposure prophylaxis (PEP) to PrEP, feeling they could benefit from or participating in mental health services. Overall, low retention in HIV preventative care was evident at the first follow-up visit (68%) and third follow-up visit (35%) after PrEP initiation. They suggest clinic services and ancillary services (such as mental health) in can help promote retention in care.