Kjøller-Hansen L, Kelbæk H, Christiansen EH, et al. - Stent treatment failure (STF) after coronary drug- eluting stent (DES) implantation was predicted by factors such as decreasing stent diameter and increasing stent length together with diabetes, previous revascularization, restenotic, bifurcation, and chronically occluded lesions.

• Data were analyzed for 2,073 patients managed with first-generation DES and followed clinically for 10 years.

• For a stent diameter ≤2.5 vs ≥3.5 mm, the STF was 23.3 vs 11.8% and target lesion failure (TLF) was 27.9 vs 18.8%.

• Stent length <20 vs >40 mm had STF 13.0 vs 29.0% and TLF 18.7 vs 34.6%.

• Using hazard ratios for the predictors, a predictive score (PS) was calculated for each lesion.

• Lesions with a PS ≤ 1.5 had a 10-year STF rate of 10%; it was 37% in lesions with PS ≥ 3.5.

• Large variations in 10-year outcomes existed based on stent size and a few patient and lesion features.