Roberts CT, et al. - Using secondary analysis of data from a randomized trial, researchers identified predictors and outcomes of early intubation in preterm infants with respiratory distress and predictors of need for brief respiratory support (≤ 1 day). Included were 564 infants with a mean (SD) gestational age of 32.0 (2.2) weeks and birth weight 1,744 (589) g; 76 infants (13.5%) were given early intubation. On multivariable analysis, intubation was predicted by lower gestational age and a higher prerandomization fraction of inspired oxygen (FiO₂). Adverse respiratory outcomes were linked to intubation. Investigators found that greater gestational age and lower FiO₂ anticipated demand for ≤ 1 day of respiratory support. Delaying the use of respiratory aid in older infants with low FiO₂ requirements may be reasonable.