Li X, et al. - In this current study, the physicians determined the incidence of appropriate implantable cardioverter-defibrillator (ICD) therapy after cardiac resynchronization therapy with defibrillator (CRT-D) generator replacement (GR). They disclosed that the improvement in left ventricular ejection fraction (LVEF) after CRT-D was associated with a significantly reduced incidence of appropriate ICD therapy. However, ventricular arrhythmia was less likely to develop with normalized LVEF in nonischemic cardiomyopathy.