Piaz GD, Mendolaro M, Mineccia M, et al. - The present study was sought to compare the predictivity for Crohn's disease recurrence of common clinical–instrumental variables when evaluated early (< 12 months) or late (> 36 months) after surgery. A total of 201 patients were included in the study. They compared clinical characteristics, post-surgical therapy, endoscopy recurrence (Rutgeerts’ score ≥ i2), and ultrasound features between subgroups who had an early or late post-surgical assessment. They performed univariate and multivariate analyses to distinguish variables associated with recurrence (clinical and surgical). According to the findings, the most informative postoperative Crohn's disease evaluation is the one done within the first year of surgery. The data illustrate that later endoscopic assessments have no prognostic value and should be done only for clinical requirements or for research purposes.