Shen L, et al. - In this prospective observational study involving 915 patients with acute ischemic stroke, researchers sought to establish a new prognostic tool for the prediction of post-stroke epilepsy (PSE) through combining the SeLECT score with IL-1β. The SeLECT score was calculated and serum IL-1β levels were measured within 24 hours of their admission. PSE was diagnosed after one unprovoked late seizure following the acute phase of stroke. According to the occurrence of PSE, all patients were divided into PSE groups and non-PSE groups. PSE occurred in 53 patients within a year of stroke onset (5.8%). Multivariate analysis showed that the SeLECT score and IL-1β were independent risk factors for PSE after adjusting for more than one comorbidity, stroke laterality, large-artery atherosclerosis, thrombolysis, age and use of statins. The combination of the SeLECT score and IL-1β had the potential to serve as a new prognostic tool for PSE prediction.