Bai S, Liu H, Wu H, et al. - Consecutive patients (n = 121) with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PPCI) within 12 h following the onset of chest pain were recruited, and were classified into Thrombolysis In Myocardial Infarction myocardial perfusion grading (TMPG) 0/1/2 group and TMPG 3 group on the basis of postprocedural TMPG in order to examine the value of serum soluble suppression of tumorigenicity 2 (sST2) baseline levels in prognosticating myocardial reperfusion in patients with STEMI who were undergoing PPCI. Univariate logistic regression analysis exhibited that risk factors of TMPG 0/1/2 were killip II-III, high levels of sST2, and brain natriuretic peptide. that sST2, as shown by multivariable logistic regression analysis, was an independent predictor of impaired myocardial reperfusion. Hence, in STEMI patients undergoing PPCI, the raised levels of sST2 on admission were correlated with impaired myocardial reperfusion.