van Beek DEC, et al. - Researchers performed this study including 100 intensive care unit (ICU) patients, to assess the predictive value of serum albumin (SA) at admission to the ICU on the cumulative dose of noradrenaline, the fluids administered, the lactate level, and mortality during the first 24 h of ICU admission. They used logistic regression to determine the link between SA and the cumulative dose of noradrenaline. Effect modifiers included age, gender, patient category, type of surgery, severe sepsis, lactate level, estimated glomerular filtration rate, c-reactive protein level, and the target mean arterial pressure. They identified SA as a significant predictor of noradrenaline dosing, the amount of fluids administered and the change in lactate level during the first 24 h of ICU admission.