Martens RM, et al. - In head and neck squamous cell carcinoma (HNSCC) patients treated by (chemo)radiotherapy, researchers identified predictive pretreatment DWI- and ¹⁸F-FDG-PET/CT-parameters for treatment failure (TF), locoregional recurrence (LR) and death. Between 2012-2017, 134 histologically proven HNSCC patients treated with (chemo)radiotherapy were included. According to this retrospective study, both DWI- and ¹⁸F-FDG-PET/CT-parameters seem to have predictive value for the failure of treatment, locoregional recurrence and death. The combination of SUV_max-PT and ADC_max-PT resulted in the better prediction of failure of treatment vs assessment of single parameters.