Predictive value of olfactory impairment for cognitive decline among cognitively normal adults
The Laryngoscope Jul 10, 2019
Windon MJ, et al. - Among cognitively normal adults, researchers characterized the predictive value of olfactory impairment (OI) for future cognitive decline. A literature search for PubMed, EMBASE, and Cochrane was included for longitudinal cohort studies after cognitively normal adults with baseline OI compared to those without OI reporting cognitive impairment or dementia. According to results, studies included were all good quality (mean score 8.7 of 9), and all studies (100%) found a statistically significant link between baseline OI and incident cognitive decline vs normosmic controls. The results obtained from this systematic review indicate that OI predicts future cognitive decline among cognitively normal adults, promoting olfactory assessment as a low-cost, minimally invasive, and widely available screening tool for use in conjunction with other tests to identify early-risk adults with dementia.
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