Toubi E, Vadasz Z, et al. - Patients with bronchial asthma, elevated total IgE levels, and autoimmunity are more likely to experience chronic spontaneous urticaria (CSU) recurrence after a full remission.

• Data were used from the CSU patient registry, which contains information on 180 patients who are monitored on a regular basis. CSU was resolved in 23 (13%) of patients within the first year.

• CSU persisted for more than 5 years in 47 (26%) of patients.

• CSU recurred in 21% of the patients after a full remission lasting ranging from 1 to 10 years (mean ± 2.9 years).

• The authors discovered bronchial asthma in 10/25 (40%) of patients with CSU recurrence, compared with 45/180 (25%) of the total CSU cohort, while exploring predictive clinical or laboratory markers.

• Furthermore, total immunoglobulin (Ig)E levels were observed to be higher in 10/25 (40%) of the recurrence group compared with 34/150 (23%) of the general CSU group.

• Anti-thyroid peroxidase antibodies were also discovered in 11/25 (44%) of the recurrence group, compared with 32/160 (20%) of the general group.