Zhang X, et al. - Researchers evaluated 150 eyes of 103 people to examine the predictive factors correlated with rate of visual field (VF) loss in open-angle glaucoma. They observed slow progression in 53.3% of eyes and confirmed rapid significant progression (CRSP) in 15.3% of eyes. In the multivariate analysis, the most significant non-VF predictor with the highest odds ratio (OR) was nerve fiber layer (NFL)-focal loss volume (FLV). They noted significant disc hemorrhage during the follow up with an OR of 2.61 for CRSP and 0.23 for slow progression for each occurrence. They suggested focal loss estimated by Fourier-domain optical coherence tomography (FD-OCT) or VF, adjacent with central corneal thickness (CCT) as strong baseline predictors for the rate of glaucoma progression.