Predictive factors for revision and survivorship analysis of a prevalent 36mm metal-on-metal total hip replacement system: A large single-centre retrospective cohort study
Journal of Arthroplasty Oct 22, 2020
Pearce O, et al. - The largest single-centre cohort of the 36mm Corail-Pinnacle metal-on-metal total hip replacements (THR) system was conducted to ascertain 10-year survivorship and identify predictors of revision. Researchers also evaluated the year of implantation given reports of manufacturing changes affecting shells made after 2006 predisposing these components to increasing wear. The Kaplan–Meier, Cox regression, and interrupted time-series analysis were applied to evaluate the impact of patient and implant-related variables, and year of implantation on revision risk. A high 10-year failure rate (16.6%) was observed with this implant, mostly due to adverse reaction to metal debris. It was shown that female gender and high femoral offset stems were significant prognosticators for all-cause revision. Although future trials to validate the effect of manufacturing discrepancies are needed, the year of implantation was not significantly correlated with an elevating number of revisions from 2007 onwards.
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